For effective apostolate MST established its regions and missionary units. Regions are those areas where MST works on a long term basis. Missionary units are those organised groups of MST that are engaged in differet apostolates in various dioceses in India and outside to cater to the missionary and pastoral needs of the place. MST has three mission regions and tens of Missionary Units Regions.

 
 
Santhome Regional House
Santhome
Santh Thoma Bhavan
Regional House Mandya
Regional House Sangli
   
 
 
UJJAIN MISSION
MANDYA MISSION
SANGLI MISSION
Area - 19401 Sq. Kms
Area - 4961 Sq. Kms
Area - 29675 Sq. Km
Population - 3926562
Population - 2155000
Population - 8655402
 
Mission Centres - 38
Mission Centres - 15
Mission Centres - 17
Missionary Units of MST
In India:
Outside India
   
  Mumbai   Tellichery
USA
  Delhi   Thamarassery Marquette Corpus Christi
  Jhansi   Ernakulam St Petersburg Chicago
  Ladakh   Irinjalakkuda Dallas  
  Ranchi   Palai
Tanzania
  Thuckalay   Kanjirappally    
  Guwahati   Trichur
South Africa
  Jammu & Srinagar   Palakkad  Port Elizabeth
  Surat   Mananthawady
Germany
  Kalyan   Belthangadi Augsburg Munster
        Eichstat PaderBorn
        Regensburg Hilesheim
       
Sweden
        Stockholm  
       
Switzerland
        Chur
       

Papua New Guinea

        Daru-kiunga
       

Austria

        Vienna
         
        Australia
         
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